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To our knowledge, this is the most comprehensive evidence to date on this issue, and while there are a number of important implications for further research, these findings provide timely information to inform regulatory strategies. PDF Version Facilitators and Barriers to Quitting Smoking or Remaining Abstinent 2021: Associations Between Nicotine Knowledge and Smoking Cessation Behaviors Among US Adults Who Smoke This study provides longitudinal evidence that among adult smokers, misperceiving nicotine as a primary cause of smoking-related diseases may be associated with reduced cessation success and lower likelihood of using less harmful nicotine products